Immunophenotyping of Acute Leukemias: Insight into Prognosis since the Outset
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چکیده
منابع مشابه
Immunophenotyping of Acute Leukemias:Insight into Prognosis since the Outset
Copyright: © 2016 Mannelli F. This is an openaccess article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. *Corresponding author: Francesco Mannelli1, MD, UF di Ematologia, Dipartimento di MedicinaSperimentale e Clinica, Università di Fire...
متن کاملImmunophenotyping of acute leukemias and myelodysplastic syndromes.
Alberto Orfao,* Francisco Ortuño, Maria de Santiago, Antonio Lopez, and Jesus San Miguel Servicio General de Citometria, Universidad de Salamanca, Salamanca, Spain Centro de Investigación del Cáncer y Departamento de Medicina, Universidad de Salamanca, Salamanca, Spain Servicio de Hematologia y Oncologia Médica, Hospital General Universitario J.M. Morales Meseguer, Murcia, Spain Servicio de Hem...
متن کاملNew methodologic approaches for immunophenotyping acute leukemias.
BACKGROUND AND OBJECTIVES Flow cytometry is nowadays the preferred method for immunophenotypic identification, enumeration and characterization of blast cells at diagnosis. Despite widespread application of standardized protocols, inter-laboratory reproducibility has still not been achieved. The complexity of diagnosis and evaluation of minimal residual disease, in immunophenotyping acute leuke...
متن کاملClassification and immunophenotyping of acute leukemias: a prospective study.
Over a period of 3-1/2 years, 86 cases of acute leukemia were analyzed by immunohistochemical (IHC) means on ficoll separated cytospin preparations of peripheral blood and/or bone marrow samples. Antibodies included in the panel were specific against Tdt, HLA-DR, CD19/CD20/CD22, CALLA (CD10), CD2, CD11C as well as against Ig heavy chains. Of 86 cases analyzed, 48 cases were of ALL, (25 of commo...
متن کاملImpact of immunophenotyping on management of acute leukemias.
BACKGROUND AND OBJECTIVE The diagnosis of acute leukemias (AL) requires a multiparametric approach in order to apply risk-adapted therapeutic protocols and appreciate the potential outcome of any given patient. Blast cells immunophenotyping is a key test in this issue, yet the information provided by immunophenotyping has become staggering, and it may be difficult to identify relevant character...
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ژورنال
عنوان ژورنال: Journal of Blood Disorders and Medicine ( ISSN 2471-5026 )
سال: 2016
ISSN: 2471-5026
DOI: 10.16966/2471-5026.105